Molecular mechanism of tumour necrosis factor alpha regulates hypocretin (orexin) expression, sleep and behaviour

Hypocretin 1 and hypocretin 2 (orexin A and B) regulate sleep, wakefulness and emotion. Tumour necrosis factor alpha (TNF‐α) is an important neuroinflammation mediator. Here, we examined the effects of TNF‐α treatment on hypocretin expression in vivo and behaviour in mice. TNF‐α decreased hypocretin...

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Detalles Bibliográficos
Autores principales: Zhan, Shuqin, Che, Pulin, Zhao, Xue‐ke, Li, Ning, Ding, Yan, Liu, Jianghong, Li, Spring, Ding, Karyn, Han, Lynn, Huang, Zhaoyang, Wu, Liyong, Wang, Yuping, Hu, Meng, Han, Xiaosi, Ding, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787512/
https://www.ncbi.nlm.nih.gov/pubmed/31386303
http://dx.doi.org/10.1111/jcmm.14566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787512/
https://www.ncbi.nlm.nih.gov/pubmed/31386303
http://dx.doi.org/10.1111/jcmm.14566

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