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Blood Vessel Patterning on Retinal Astrocytes Requires Endothelial Flt-1 (VEGFR-1)

Feedback mechanisms are critical components of many pro-angiogenic signaling pathways that keep vessel growth within a functional range. The Vascular Endothelial Growth Factor-A (VEGF-A) pathway utilizes the decoy VEGF-A receptor Flt-1 to provide negative feedback regulation of VEGF-A signaling. In...

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Detalles Bibliográficos
Autores principales: Chappell, John C., Darden, Jordan, Payne, Laura Beth, Fink, Kathryn, Bautch, Victoria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787756/
https://www.ncbi.nlm.nih.gov/pubmed/31500294
http://dx.doi.org/10.3390/jdb7030018