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Targeted Approaches to Inhibit Sialylation of Multiple Myeloma in the Bone Marrow Microenvironment

Aberrant glycosylation modulates different aspects of tumor biology, and it has long been recognized as a hallmark of cancer. Among the different forms of glycosylation, sialylation, the addition of sialic acid to underlying oligosaccharides, is often dysregulated in cancer. Increased expression of...

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Detalles Bibliográficos
Autores principales: Natoni, Alessandro, Bohara, Raghvendra, Pandit, Abhay, O'Dwyer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787837/
https://www.ncbi.nlm.nih.gov/pubmed/31637237
http://dx.doi.org/10.3389/fbioe.2019.00252