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Thermal Dissociation Assay for Time-Resolved Fluorescence Detection of Protein Post-Translational Modifications

[Image: see text] Post-translational modifications (PTMs) of proteins provide an important mechanism for cell signal transduction control. Impaired PTM control is a key feature in multiple different disease states, and thus the enzyme-controlling PTMs have drawn attention as highly promising drug ta...

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Detalles Bibliográficos
Autores principales: Eskonen, Ville, Tong-Ochoa, Natalia, Valtonen, Salla, Kopra, Kari, Härmä, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787904/
https://www.ncbi.nlm.nih.gov/pubmed/31616828
http://dx.doi.org/10.1021/acsomega.9b02134