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Polymorphisms of MTHFR and TYMS predict capecitabine-induced hand-foot syndrome in patients with metastatic breast cancer

BACKGROUND: Breast cancer is a global problem, and a large number of new cases are diagnosed every year. Capecitabine is effective in patients with metastatic breast cancer (MBC). Hand-foot syndrome (HFS) is a common adverse effect of capecitabine. In this study, we investigated the association betw...

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Detalles Bibliográficos
Autores principales: Lin, Shaoyan, Yue, Jian, Guan, Xiuwen, Yuan, Peng, Wang, Jiayu, Luo, Yang, Fan, Ying, Cai, Ruigang, Li, Qiao, Chen, Shanshan, Zhang, Pin, Li, Qing, Ma, Fei, Xu, Binghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787984/
https://www.ncbi.nlm.nih.gov/pubmed/31601265
http://dx.doi.org/10.1186/s40880-019-0399-z