Conservation of Atypical Allostery in C. elegans UDP-Glucose Dehydrogenase

[Image: see text] Human UDP-glucose dehydrogenase (hUGDH) oxidizes uridine diphosphate (UDP)-glucose to UDP-glucuronic acid, an essential substrate in the phase II metabolism of drugs. The activity of hUGDH is controlled by an atypical allosteric mechanism in which the feedback inhibitor UDP-xylose...

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Detalles Bibliográficos
Autores principales: Beattie, Nathaniel R., Keul, Nicholas D., Hicks Sirmans, Tiffany N., McDonald, Weston E., Talmadge, Trevor M., Taujale, Rahil, Kannan, Natarajan, Wood, Zachary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788056/
https://www.ncbi.nlm.nih.gov/pubmed/31616809
http://dx.doi.org/10.1021/acsomega.9b01565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788056/
https://www.ncbi.nlm.nih.gov/pubmed/31616809
http://dx.doi.org/10.1021/acsomega.9b01565

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