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Enhanced IFN-γ, but not IL-2, response to Mycobacterium tuberculosis antigens in HIV/latent TB co-infected patients on long-term HAART

BACKGROUND: HIV-infected individuals with latent TB infection are at increased risk of developing active TB. HAART greatly reduces the incidence rate of TB in HIV-infected patients and reconstitutes Mycobacterium tuberculosis (M. tuberculosis)-specific immune response in the first 12 months of thera...

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Detalles Bibliográficos
Autores principales: Desalegn, Girmay, Tsegaye, Aster, Gebreegziabiher, Dawit, Aseffa, Abraham, Howe, Rawleigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788090/
https://www.ncbi.nlm.nih.gov/pubmed/31601184
http://dx.doi.org/10.1186/s12865-019-0317-9