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Enhanced uptake, high selective and microtubule disrupting activity of carbohydrate fused pyrano-pyranones derived from natural coumarins attributes to its anti-malarial potential

BACKGROUND: Malaria is one of the deadliest infectious diseases caused by protozoan parasite of Plasmodium spp. Increasing resistance to anti-malarials has become global threat in control of the disease and demands for novel anti-malarial interventions. Naturally-occurring coumarins, which belong to...

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Detalles Bibliográficos
Autores principales: Gupta, Sonal, Khan, Juveria, Kumari, Priti, Narayana, Chintam, Ayana, R., Chakrabarti, Malabika, Sagar, Ram, Singh, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788091/
https://www.ncbi.nlm.nih.gov/pubmed/31601218
http://dx.doi.org/10.1186/s12936-019-2971-z