Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans

The ability to introduce targeted edits in the genome of model organisms is revolutionizing the field of genetics. State-of-the-art methods for precision genome editing use RNA-guided endonucleases to create double-strand breaks (DSBs) and DNA templates containing the edits to repair the DSBs. Follo...

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Detalles Bibliográficos
Autores principales: Paix, Alexandre, Folkmann, Andrew, Seydoux, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788293/
https://www.ncbi.nlm.nih.gov/pubmed/28392263
http://dx.doi.org/10.1016/j.ymeth.2017.03.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788293/
https://www.ncbi.nlm.nih.gov/pubmed/28392263
http://dx.doi.org/10.1016/j.ymeth.2017.03.023

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