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Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans
The ability to introduce targeted edits in the genome of model organisms is revolutionizing the field of genetics. State-of-the-art methods for precision genome editing use RNA-guided endonucleases to create double-strand breaks (DSBs) and DNA templates containing the edits to repair the DSBs. Follo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788293/ https://www.ncbi.nlm.nih.gov/pubmed/28392263 http://dx.doi.org/10.1016/j.ymeth.2017.03.023 |