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Development and Application of Sub-Mitochondrial Targeted Ca(2 +) Biosensors

Mitochondrial Ca(2+) uptake into the mitochondrial matrix is a well-established mechanism. However, the sub-organellar Ca(2+) kinetics remain elusive. In the present work we identified novel site-specific targeting sequences for the intermembrane space (IMS) and the cristae lumen (CL). We used these...

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Detalles Bibliográficos
Autores principales: Waldeck-Weiermair, Markus, Gottschalk, Benjamin, Madreiter-Sokolowski, Corina T., Ramadani-Muja, Jeta, Ziomek, Gabriela, Klec, Christiane, Burgstaller, Sandra, Bischof, Helmut, Depaoli, Maria R., Eroglu, Emrah, Malli, Roland, Graier, Wolfgang F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788349/
https://www.ncbi.nlm.nih.gov/pubmed/31636543
http://dx.doi.org/10.3389/fncel.2019.00449