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Development and Application of Sub-Mitochondrial Targeted Ca(2 +) Biosensors
Mitochondrial Ca(2+) uptake into the mitochondrial matrix is a well-established mechanism. However, the sub-organellar Ca(2+) kinetics remain elusive. In the present work we identified novel site-specific targeting sequences for the intermembrane space (IMS) and the cristae lumen (CL). We used these...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788349/ https://www.ncbi.nlm.nih.gov/pubmed/31636543 http://dx.doi.org/10.3389/fncel.2019.00449 |