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Seconds-resolved pharmacokinetic measurements of the chemotherapeutic irinotecan in situ in the living body

The ability to measure drugs in the body rapidly and in real time would advance both our understanding of pharmacokinetics and our ability to optimally dose and deliver pharmacological therapies. To this end, we are developing electrochemical aptamer-based (E-AB) sensors, a seconds-resolved platform...

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Detalles Bibliográficos
Autores principales: Idili, Andrea, Arroyo-Currás, Netzahualcóyotl, Ploense, Kyle L., Csordas, Andrew T., Kuwahara, Masayasu, Kippin, Tod E., Plaxco, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788505/
https://www.ncbi.nlm.nih.gov/pubmed/31673321
http://dx.doi.org/10.1039/c9sc01495k