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Stabilization of α-synuclein oligomers using formaldehyde

The group of neurodegenerative diseases, Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) all exhibit inclusions containing amyloid-type α-synuclein (α-syn) aggregates within degenerating brain cells. α-syn also exists as soluble oligomeric species th...

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Detalles Bibliográficos
Autores principales: Ruesink, Harm, Reimer, Lasse, Gregersen, Emil, Moeller, Arne, Betzer, Cristine, Jensen, Poul Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788717/
https://www.ncbi.nlm.nih.gov/pubmed/31603909
http://dx.doi.org/10.1371/journal.pone.0216764