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Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

The impact of glucose metabolism on muscle regeneration remains unresolved. We identify glucose metabolism as a crucial driver of histone acetylation and myogenic cell fate. We use single-cell mass cytometry (CyTOF) and flow cytometry to characterize the histone acetylation and metabolic states of q...

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Detalles Bibliográficos
Autores principales: Yucel, Nora, Wang, Yu Xin, Mai, Thach, Porpiglia, Ermelinda, Lund, Peder J., Markov, Glenn, Garcia, Benjamin A., Bendall, Sean C., Angelo, Michael, Blau, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788807/
https://www.ncbi.nlm.nih.gov/pubmed/31242425
http://dx.doi.org/10.1016/j.celrep.2019.05.092