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Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function
The impact of glucose metabolism on muscle regeneration remains unresolved. We identify glucose metabolism as a crucial driver of histone acetylation and myogenic cell fate. We use single-cell mass cytometry (CyTOF) and flow cytometry to characterize the histone acetylation and metabolic states of q...
Autores principales: | Yucel, Nora, Wang, Yu Xin, Mai, Thach, Porpiglia, Ermelinda, Lund, Peder J., Markov, Glenn, Garcia, Benjamin A., Bendall, Sean C., Angelo, Michael, Blau, Helen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788807/ https://www.ncbi.nlm.nih.gov/pubmed/31242425 http://dx.doi.org/10.1016/j.celrep.2019.05.092 |
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