Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) have promising utility in prevention and treatment of HIV-1 infection, and several are currently undergoing clinical trials. Due to the high sequence diversity and mutation rate of HIV-1, viral isolates are often...

Descripción completa

Detalles Bibliográficos
Autores principales: Rawi, Reda, Mall, Raghvendra, Shen, Chen-Hsiang, Farney, S. Katie, Shiakolas, Andrea, Zhou, Jing, Bensmail, Halima, Chun, Tae-Wook, Doria-Rose, Nicole A., Lynch, Rebecca M., Mascola, John R., Kwong, Peter D., Chuang, Gwo-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789020/
https://www.ncbi.nlm.nih.gov/pubmed/31604961
http://dx.doi.org/10.1038/s41598-019-50635-w