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Second messenger Ap(4)A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells
Signal transduction systems enable organisms to monitor their external environments and accordingly adjust the cellular processes. In mast cells, the second messenger Ap(4)A binds to the histidine triad nucleotide-binding protein 1 (HINT1), disrupts its interaction with the microphthalmia-associated...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789022/ https://www.ncbi.nlm.nih.gov/pubmed/31604935 http://dx.doi.org/10.1038/s41467-019-12710-8 |