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Second messenger Ap(4)A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells

Signal transduction systems enable organisms to monitor their external environments and accordingly adjust the cellular processes. In mast cells, the second messenger Ap(4)A binds to the histidine triad nucleotide-binding protein 1 (HINT1), disrupts its interaction with the microphthalmia-associated...

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Detalles Bibliográficos
Autores principales: Yu, Jing, Liu, Zaizhou, Liang, Yuanyuan, Luo, Feng, Zhang, Jie, Tian, Cuiping, Motzik, Alex, Zheng, Mengmeng, Kang, Jingwu, Zhong, Guisheng, Liu, Cong, Fang, Pengfei, Guo, Min, Razin, Ehud, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789022/
https://www.ncbi.nlm.nih.gov/pubmed/31604935
http://dx.doi.org/10.1038/s41467-019-12710-8