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Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC

In mycobacteria, transcriptional activator PafBC is responsible for upregulating the majority of genes induced by DNA damage. Understanding the mechanism of PafBC activation is impeded by a lack of structural information on this transcription factor that contains a widespread, but poorly understood...

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Detalles Bibliográficos
Autores principales: Müller, Andreas U., Leibundgut, Marc, Ban, Nenad, Weber-Ban, Eilika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789036/
https://www.ncbi.nlm.nih.gov/pubmed/31604936
http://dx.doi.org/10.1038/s41467-019-12567-x