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Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC
In mycobacteria, transcriptional activator PafBC is responsible for upregulating the majority of genes induced by DNA damage. Understanding the mechanism of PafBC activation is impeded by a lack of structural information on this transcription factor that contains a widespread, but poorly understood...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789036/ https://www.ncbi.nlm.nih.gov/pubmed/31604936 http://dx.doi.org/10.1038/s41467-019-12567-x |