HCMV-encoded US7 and US8 act as antagonists of innate immunity by distinctively targeting TLR-signaling pathways

The mechanisms by which many human cytomegalovirus (HCMV)-encoded proteins help the virus to evade immune surveillance remain poorly understood. In particular, it is unknown whether HCMV proteins arrest Toll-like receptor (TLR) signaling pathways required for antiviral defense. Here, we report that...

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Detalles Bibliográficos
Autores principales: Park, Areum, Ra, Eun A., Lee, Taeyun A., Choi, Hyun jin, Lee, Eunhye, Kang, Sujin, Seo, Jun-Young, Lee, Sungwook, Park, Boyoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789044/
https://www.ncbi.nlm.nih.gov/pubmed/31604943
http://dx.doi.org/10.1038/s41467-019-12641-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789044/
https://www.ncbi.nlm.nih.gov/pubmed/31604943
http://dx.doi.org/10.1038/s41467-019-12641-4

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