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Development of a simple and high-yielding fed-batch process for the production of porcine circovirus type 2 virus-like particle subunit vaccine

The cap protein is encoded by the orf2 gene of porcine circovirus type 2 (PCV2) has the main antigen epitope of PCV2 and can form virus-like particles (VLPs), which are expressed in insect cells. PCV2-VLPs can effectively inhibit PCV2 replication as a subunit vaccine. In this study, a robust and rel...

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Detalles Bibliográficos
Autores principales: Cao, Wenlong, Cao, Hui, Yi, Xiaoping, Zhuang, Yingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789058/
https://www.ncbi.nlm.nih.gov/pubmed/31605297
http://dx.doi.org/10.1186/s13568-019-0880-8