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Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
The filamentous bacteriophage fd bind a cell target with exquisite specificity through its few copies of display peptides, whereas nanoparticles functionalized with hundreds to thousands of synthetically generated phage display peptides exhibit variable and often-weak target binding. We hypothesise...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789111/ https://www.ncbi.nlm.nih.gov/pubmed/31604928 http://dx.doi.org/10.1038/s41467-019-12554-2 |