Cargando…

Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide

The filamentous bacteriophage fd bind a cell target with exquisite specificity through its few copies of display peptides, whereas nanoparticles functionalized with hundreds to thousands of synthetically generated phage display peptides exhibit variable and often-weak target binding. We hypothesise...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Lin-Ping, Ahmadvand, Davoud, Su, Junan, Hall, Arnaldur, Tan, Xiaolong, Farhangrazi, Z. Shadi, Moghimi, S. Moein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789111/
https://www.ncbi.nlm.nih.gov/pubmed/31604928
http://dx.doi.org/10.1038/s41467-019-12554-2