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Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients

Systemic oxidative stress plays a key role in the development of chronic heart failure (CHF). We tested the hypothesis that mitochondrial reactive oxygen species (ROS) generation in circulating peripheral blood mononuclear cells (PBMCs) contributes to CHF progression. A total of 31 patients who had...

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Detalles Bibliográficos
Autores principales: Shirakawa, Ryosuke, Yokota, Takashi, Nakajima, Takayuki, Takada, Shingo, Yamane, Miwako, Furihata, Takaaki, Maekawa, Satoshi, Nambu, Hideo, Katayama, Takashi, Fukushima, Arata, Saito, Akimichi, Ishimori, Naoki, Dela, Flemming, Kinugawa, Shintaro, Anzai, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789126/
https://www.ncbi.nlm.nih.gov/pubmed/31605012
http://dx.doi.org/10.1038/s41598-019-51298-3