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Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients
Systemic oxidative stress plays a key role in the development of chronic heart failure (CHF). We tested the hypothesis that mitochondrial reactive oxygen species (ROS) generation in circulating peripheral blood mononuclear cells (PBMCs) contributes to CHF progression. A total of 31 patients who had...
Autores principales: | Shirakawa, Ryosuke, Yokota, Takashi, Nakajima, Takayuki, Takada, Shingo, Yamane, Miwako, Furihata, Takaaki, Maekawa, Satoshi, Nambu, Hideo, Katayama, Takashi, Fukushima, Arata, Saito, Akimichi, Ishimori, Naoki, Dela, Flemming, Kinugawa, Shintaro, Anzai, Toshihisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789126/ https://www.ncbi.nlm.nih.gov/pubmed/31605012 http://dx.doi.org/10.1038/s41598-019-51298-3 |
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