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Shortened nuclear matrix attachment regions are sufficient for replication and maintenance of episomes in mammalian cells
Matrix attachment regions (MARs) can mediate the replication of vector episomes in mammalian cells; however, the molecular mode of action remains unclear. Here, we assessed the characteristics of MARs and the mechanism that mediates episomal vector replication in mammalian cells. Five shortened subf...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789156/ https://www.ncbi.nlm.nih.gov/pubmed/31509492 http://dx.doi.org/10.1091/mbc.E19-02-0108 |