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Kinetochore-mediated outward force promotes spindle pole separation in fission yeast

Bipolar spindles are organized by motor proteins that generate microtubule-­dependent forces to separate the two spindle poles. The fission yeast Cut7 (kinesin-5) is a plus-end-directed motor that generates the outward force to separate the two spindle poles, whereas the minus-end-directed motor Pkl...

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Detalles Bibliográficos
Autores principales: Shirasugi, Yutaka, Sato, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789161/
https://www.ncbi.nlm.nih.gov/pubmed/31532702
http://dx.doi.org/10.1091/mbc.E19-07-0366