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Attenuation of Zika Virus by Passage in Human HeLa Cells

Zika virus (ZIKV) is a mosquito-borne Flavivirus. Previous studies have shown that mosquito-transmitted flaviviruses, including yellow fever, Japanese encephalitis, and West Nile viruses, could be attenuated by serial passaging in human HeLa cells. Therefore, it was hypothesized that wild-type ZIKV...

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Detalles Bibliográficos
Autores principales: Li, Li, Collins, Natalie D., Widen, Steven G., Davis, Emily H., Kaiser, Jaclyn A., White, Mellodee M., Greenberg, M. Banks, Barrett, Alan D. T., Bourne, Nigel, Sarathy, Vanessa V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789458/
https://www.ncbi.nlm.nih.gov/pubmed/31434319
http://dx.doi.org/10.3390/vaccines7030093