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HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System

The HFE gene (OMIM 235200), most commonly associated with the genetic iron overload disorder Hemochromatosis, was identified by Feder et al. in 1996, as a major histocompatibilty complex (MHC) class I like gene, first designated human leukocyte antigen-H (HLA-H). This discovery was thus accomplished...

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Detalles Bibliográficos
Autores principales: Porto, Graça, Cruz, Eugénia, Teles, Maria José, de Sousa, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789554/
https://www.ncbi.nlm.nih.gov/pubmed/31443397
http://dx.doi.org/10.3390/ph12030122