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A Visualization Tool for Cryo-EM Protein Validation with an Unsupervised Machine Learning Model in Chimera Platform

Background: Cryo-electron microscopy (cryo-EM) has become a major technique for protein structure determination. However, due to the low quality of cryo-EM density maps, many protein structures derived from cryo-EM contain outliers introduced during the modeling process. The current protein model va...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Baker, Brandon, Santos, Eduardo, Sheep, Michell, Daftarian, Darius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789601/
https://www.ncbi.nlm.nih.gov/pubmed/31390767
http://dx.doi.org/10.3390/medicines6030086