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A Visualization Tool for Cryo-EM Protein Validation with an Unsupervised Machine Learning Model in Chimera Platform
Background: Cryo-electron microscopy (cryo-EM) has become a major technique for protein structure determination. However, due to the low quality of cryo-EM density maps, many protein structures derived from cryo-EM contain outliers introduced during the modeling process. The current protein model va...
Autores principales: | Chen, Lin, Baker, Brandon, Santos, Eduardo, Sheep, Michell, Daftarian, Darius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789601/ https://www.ncbi.nlm.nih.gov/pubmed/31390767 http://dx.doi.org/10.3390/medicines6030086 |
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