Long-Lasting Mucosal and Systemic Immunity against Influenza A Virus Is Significantly Prolonged and Protective by Nasal Whole Influenza Immunization with Mucosal Adjuvant N3 and DNA-Plasmid Expressing Flagellin in Aging In- and Outbred Mice

Background: Vaccination is commonly used to prevent and control influenza infection in humans. However, improvements in the ease of delivery and strength of immunogenicity could markedly improve herd immunity. The aim of this pre-clinical study is to test the potential improvements to existing intra...

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Detalles Bibliográficos
Autores principales: Hinkula, Jorma, Nyström, Sanna, Devito, Claudia, Bråve, Andreas, Applequist, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789645/
https://www.ncbi.nlm.nih.gov/pubmed/31315253
http://dx.doi.org/10.3390/vaccines7030064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789645/
https://www.ncbi.nlm.nih.gov/pubmed/31315253
http://dx.doi.org/10.3390/vaccines7030064

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