The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells

Ribonucleotide reductase (RR) is the rate-limiting enzyme that controls the deoxynucleotide triphosphate synthesis and it is an important target of cancer treatment, since it is expressed in tumor cells in proportion to their proliferation rate, their invasiveness and poor prognosis. Didox, a deriva...

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Detalles Bibliográficos
Autores principales: Asperti, Michela, Cantamessa, Luca, Ghidinelli, Simone, Gryzik, Magdalena, Denardo, Andrea, Giacomini, Arianna, Longhi, Giovanna, Fanzani, Alessandro, Arosio, Paolo, Poli, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789654/
https://www.ncbi.nlm.nih.gov/pubmed/31480699
http://dx.doi.org/10.3390/ph12030129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789654/
https://www.ncbi.nlm.nih.gov/pubmed/31480699
http://dx.doi.org/10.3390/ph12030129

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