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The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells
Ribonucleotide reductase (RR) is the rate-limiting enzyme that controls the deoxynucleotide triphosphate synthesis and it is an important target of cancer treatment, since it is expressed in tumor cells in proportion to their proliferation rate, their invasiveness and poor prognosis. Didox, a deriva...
Autores principales: | Asperti, Michela, Cantamessa, Luca, Ghidinelli, Simone, Gryzik, Magdalena, Denardo, Andrea, Giacomini, Arianna, Longhi, Giovanna, Fanzani, Alessandro, Arosio, Paolo, Poli, Maura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789654/ https://www.ncbi.nlm.nih.gov/pubmed/31480699 http://dx.doi.org/10.3390/ph12030129 |
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