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What is Normalization? The Strategies Employed in Top-Down and Bottom-Up Proteome Analysis Workflows

The accurate quantification of changes in the abundance of proteins is one of the main applications of proteomics. The maintenance of accuracy can be affected by bias and error that can occur at many points in the experimental process, and normalization strategies are crucial to attempt to overcome...

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Detalles Bibliográficos
Autores principales: O’Rourke, Matthew B., Town, Stephanie E. L., Dalla, Penelope V., Bicknell, Fiona, Koh Belic, Naomi, Violi, Jake P., Steele, Joel R., Padula, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789750/
https://www.ncbi.nlm.nih.gov/pubmed/31443461
http://dx.doi.org/10.3390/proteomes7030029