Novel Treatment Targets Based on Insights in the Etiology of Depression: Role of IL-6 Trans-Signaling and Stress-Induced Elevation of Glutamate and ATP

Inflammation and psychological stress are risk factors for major depression and suicide. Both increase central glutamate levels and activate the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. Both factors also affect the function of the chloride transporters, Na-K-Cl-cotrans...

Descripción completa

Detalles Bibliográficos
Autor principal: Kalkman, Hans O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789839/
https://www.ncbi.nlm.nih.gov/pubmed/31362361
http://dx.doi.org/10.3390/ph12030113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789839/
https://www.ncbi.nlm.nih.gov/pubmed/31362361
http://dx.doi.org/10.3390/ph12030113

Ejemplares similares