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Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer’s Disease

Previous systems-based proteomic approaches have characterized alterations in protein co-expression networks of unfractionated asymptomatic (AsymAD) and symptomatic Alzheimer’s disease (AD) brains. However, it remains unclear how sample fractionation and sub-proteomic analysis influences the organiz...

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Detalles Bibliográficos
Autores principales: Higginbotham, Lenora, Dammer, Eric B., Duong, Duc M., Modeste, Erica, Montine, Thomas J., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789842/
https://www.ncbi.nlm.nih.gov/pubmed/31461916
http://dx.doi.org/10.3390/proteomes7030030