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Quantifying Fluorescently Labeled Ceramide Levels in Human Sarcoma Cell Lines in Response to a Sphingomyelin Synthase Inhibitor

Sphingolipid metabolism is an important process in sustaining the growth needs of rapidly dividing cancer cells. Enzymes that synthesize sphingolipids have become attractive targets in cancer pharmacology. Ceramide is a precursor for synthesizing sphingolipids such as sphingomyelin, sphingosine-1-ph...

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Detalles Bibliográficos
Autores principales: Pashikanti, Srinath, Afrin, Farjana, Meldrum, Trevor C., Stegelmeier, John L., Pavek, Adriene, Habashi, Yashar A., Fatema, Kaniz, Barrott, Jared J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789850/
https://www.ncbi.nlm.nih.gov/pubmed/31480447
http://dx.doi.org/10.3390/mps2030076