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Quantifying Fluorescently Labeled Ceramide Levels in Human Sarcoma Cell Lines in Response to a Sphingomyelin Synthase Inhibitor
Sphingolipid metabolism is an important process in sustaining the growth needs of rapidly dividing cancer cells. Enzymes that synthesize sphingolipids have become attractive targets in cancer pharmacology. Ceramide is a precursor for synthesizing sphingolipids such as sphingomyelin, sphingosine-1-ph...
Autores principales: | Pashikanti, Srinath, Afrin, Farjana, Meldrum, Trevor C., Stegelmeier, John L., Pavek, Adriene, Habashi, Yashar A., Fatema, Kaniz, Barrott, Jared J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789850/ https://www.ncbi.nlm.nih.gov/pubmed/31480447 http://dx.doi.org/10.3390/mps2030076 |
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