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Reduced Renal Colonization and Enhanced Protection by Leptospiral Factor H Binding Proteins as a Multisubunit Vaccine against Leptospirosis in Hamsters

Subunit vaccines conferring complete protection against leptospirosis are not currently available. The interactions of factor H binding proteins (FHBPs) on pathogenic leptospires and host factor H are crucial for immune evasion by inhibition of complement-mediated killing. The inhibition of these in...

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Detalles Bibliográficos
Autores principales: Techawiwattanaboon, Teerasit, Barnier-Quer, Christophe, Palaga, Tanapat, Jacquet, Alain, Collin, Nicolas, Sangjun, Noppadon, Komanee, Pat, Piboonpocanun, Surapon, Patarakul, Kanitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789851/
https://www.ncbi.nlm.nih.gov/pubmed/31443566
http://dx.doi.org/10.3390/vaccines7030095