The Increase of the Magnitude of Spontaneous Viral Blips in Some Participants of Phase II Clinical Trial of Therapeutic Optimized HIV DNA Vaccine Candidate

We developed a candidate DNA vaccine called “DNA-4”consisting of 4 plasmid DNAs encoding Nef, Gag, Pol(rt), and gp140 HIV-1 proteins. The vaccine was found to be safe and immunogenic in a phase I clinical trial. Here we present the results of a phase II clinical trial of “DNA-4”. This was a multicen...

Descripción completa

Detalles Bibliográficos
Autores principales: Akulova, Ekaterina, Murashev, Boris, Verevochkin, Sergey, Masharsky, Alexey, Al-Shekhadat, Ruslan, Poddubnyy, Valeriy, Zozulya, Olga, Vostokova, Natalia, Kozlov, Andrei P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789887/
https://www.ncbi.nlm.nih.gov/pubmed/31434305
http://dx.doi.org/10.3390/vaccines7030092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789887/
https://www.ncbi.nlm.nih.gov/pubmed/31434305
http://dx.doi.org/10.3390/vaccines7030092

Ejemplares similares