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African trypanosomes expressing multiple VSGs are rapidly eliminated by the host immune system

Trypanosoma brucei parasites successfully evade the host immune system by periodically switching the dense coat of variant surface glycoprotein (VSG) at the cell surface. Each parasite expresses VSGs in a monoallelic fashion that is tightly regulated. The consequences of exposing multiple VSGs durin...

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Detalles Bibliográficos
Autores principales: Aresta-Branco, Francisco, Sanches-Vaz, Margarida, Bento, Fabio, Rodrigues, João A., Figueiredo, Luisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789922/
https://www.ncbi.nlm.nih.gov/pubmed/31554700
http://dx.doi.org/10.1073/pnas.1905120116