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Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus

Cedar virus (CedV) is a bat-borne henipavirus related to Nipah virus (NiV) and Hendra virus (HeV), zoonotic agents of fatal human disease. CedV receptor-binding protein (G) shares only ∼30% sequence identity with those of NiV and HeV, although they can all use ephrin-B2 as an entry receptor. We demo...

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Detalles Bibliográficos
Autores principales: Laing, Eric D., Navaratnarajah, Chanakha K., Cheliout Da Silva, Sofia, Petzing, Stephanie R., Xu, Yan, Sterling, Spencer L., Marsh, Glenn A., Wang, Lin-Fa, Amaya, Moushimi, Nikolov, Dimitar B., Cattaneo, Roberto, Broder, Christopher C., Xu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789926/
https://www.ncbi.nlm.nih.gov/pubmed/31548390
http://dx.doi.org/10.1073/pnas.1911773116