A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells

Mechanoelectrical transducer (MET) currents were recorded from cochlear hair cells in mice with mutations of transmembrane channel-like protein TMC1 to study the effects on MET channel properties. We characterized a Tmc1 mouse with a single-amino-acid mutation (D569N), homologous to a dominant human...

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Detalles Bibliográficos
Autores principales: Beurg, Maryline, Barlow, Amanda, Furness, David N., Fettiplace, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789967/
https://www.ncbi.nlm.nih.gov/pubmed/31548403
http://dx.doi.org/10.1073/pnas.1908058116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789967/
https://www.ncbi.nlm.nih.gov/pubmed/31548403
http://dx.doi.org/10.1073/pnas.1908058116

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