Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy

The contractile perivascular cells, pericytes (PC), are hijacked by glioblastoma (GB) to facilitate tumor progression. PC’s protumorigenic function requires direct interaction with tumor cells and contributes to the establishment of immunotolerance to tumor growth. Cancer cells up-regulate their own...

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Detalles Bibliográficos
Autores principales: Valdor, Rut, García-Bernal, David, Riquelme, Dolores, Martinez, Carlos M., Moraleda, Jose M., Cuervo, Ana Maria, Macian, Fernando, Martinez, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789971/
https://www.ncbi.nlm.nih.gov/pubmed/31548426
http://dx.doi.org/10.1073/pnas.1903542116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789971/
https://www.ncbi.nlm.nih.gov/pubmed/31548426
http://dx.doi.org/10.1073/pnas.1903542116

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