MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions

scRNA-seq profiles each represent a highly partial sample of mRNA molecules from a unique cell that can never be resampled, and robust analysis must separate the sampling effect from biological variance. We describe a methodology for partitioning scRNA-seq datasets into metacells: disjoint and homog...

Descripción completa

Detalles Bibliográficos
Autores principales: Baran, Yael, Bercovich, Akhiad, Sebe-Pedros, Arnau, Lubling, Yaniv, Giladi, Amir, Chomsky, Elad, Meir, Zohar, Hoichman, Michael, Lifshitz, Aviezer, Tanay, Amos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790056/
https://www.ncbi.nlm.nih.gov/pubmed/31604482
http://dx.doi.org/10.1186/s13059-019-1812-2

Ejemplares similares

Ejemplares similares