Icotinib-resistant HCC827 cells produce exosomes with mRNA MET oncogenes and mediate the migration and invasion of NSCLC

BACKGROUND: Icotinib has been widely used in patients with non-small cell lung cancer (NSCLC), and have significantly enhanced the overall survival rate of NSCLC patients. However, acquired drug resistance limits its clinical efficacy. Tumor cell-derived exosomes have been reported to participate in...

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Detalles Bibliográficos
Autores principales: Yu, Yiming, Abudula, Maidinaimu, Li, Chaofen, Chen, Zhongbo, Zhang, Yun, Chen, Yichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790059/
https://www.ncbi.nlm.nih.gov/pubmed/31606039
http://dx.doi.org/10.1186/s12931-019-1202-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790059/
https://www.ncbi.nlm.nih.gov/pubmed/31606039
http://dx.doi.org/10.1186/s12931-019-1202-z

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