Optimizing drug selection in psychopharmacology based on 40 significant CYP2C19- and CYP2D6-biased adverse drug reactions of selective serotonin reuptake inhibitors

BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed class of drugs in the practice of psychiatry. Cytochrome P450 (CYP) 2C19 and CYP2D6 are established as clinically relevant drug metabolizing enzymes (DMEs) that influence the pharmacokinetics of SSRIs an...

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Detalles Bibliográficos
Autor principal: Eugene, Andy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790106/
https://www.ncbi.nlm.nih.gov/pubmed/31616600
http://dx.doi.org/10.7717/peerj.7860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790106/
https://www.ncbi.nlm.nih.gov/pubmed/31616600
http://dx.doi.org/10.7717/peerj.7860

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