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Optimizing drug selection in psychopharmacology based on 40 significant CYP2C19- and CYP2D6-biased adverse drug reactions of selective serotonin reuptake inhibitors
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed class of drugs in the practice of psychiatry. Cytochrome P450 (CYP) 2C19 and CYP2D6 are established as clinically relevant drug metabolizing enzymes (DMEs) that influence the pharmacokinetics of SSRIs an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PeerJ Inc.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790106/ https://www.ncbi.nlm.nih.gov/pubmed/31616600 http://dx.doi.org/10.7717/peerj.7860 |