N(10)‐carbonyl‐substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress

During some investigations into the mechanism of nitric oxide consumption by brain preparations, several potent inhibitors of this process were identified. Subsequent tests revealed the compounds act by inhibiting lipid peroxidation, a trigger for a form of regulated cell death known as ferroptosis....

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Detalles Bibliográficos
Autores principales: Keynes, Robert G., Karchevskaya, Anastasia, Riddall, Dieter, Griffiths, Charmaine H., Bellamy, Tomas C., Chan, A. W. Edith, Selwood, David L., Garthwaite, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790564/
https://www.ncbi.nlm.nih.gov/pubmed/31127979
http://dx.doi.org/10.1111/cbdd.13572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790564/
https://www.ncbi.nlm.nih.gov/pubmed/31127979
http://dx.doi.org/10.1111/cbdd.13572

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