Cornea nerve fibre state determines analgesic response to tapentadol in fibromyalgia patients without effective endogenous pain modulation

BACKGROUND: Tapentadol is a centrally acting analgesic with μ‐agonistic activity combined with noradrenaline reuptake inhibition. Its mechanism of action relies on improvement of descending pain inhibition. In the current study, tapentadol's ability to enhance conditioned pain modulation (CPM,...

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Detalles Bibliográficos
Autores principales: van de Donk, Tine, van Velzen, Monique, Dahan, Albert, Niesters, Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790686/
https://www.ncbi.nlm.nih.gov/pubmed/31162787
http://dx.doi.org/10.1002/ejp.1435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790686/
https://www.ncbi.nlm.nih.gov/pubmed/31162787
http://dx.doi.org/10.1002/ejp.1435

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