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Metabolite profiling of guanfacine in plasma and urine of healthy Japanese subjects after oral administration of guanfacine extended‐release tablets

Guanfacine is used for the treatment of attention‐deficit/hyperactivity disorder (ADHD). Using liquid chromatography–tandem mass spectrometry (LC–MS/MS), metabolite profiling of guanfacine was performed in plasma and urine collected from healthy Japanese adults following repeated oral administration...

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Detalles Bibliográficos
Autores principales: Inoue, Yuji, Morita, Hirotoshi, Nozawa, Kohei, Kanazu, Takushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790749/
https://www.ncbi.nlm.nih.gov/pubmed/31313320
http://dx.doi.org/10.1002/bdd.2201